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A 65-year-old man is admitted to the hospital for a knee replacement.

A 65-year-old man is admitted to the hospital for a knee replacement. On physical examination, cervical lymphadenopathy was noted. His presurgical CBC values indicated an increased WBC count with relative and absolute lymphocytosis. The technician also made a note of smudge cells present. In your post, consider the following questions:

What is the patient’s probable diagnosis based on this information?

What is a smudge cell?

What is the ideal treatment plan?

Solution Preview


(a) based on information probable diagnosis is Chronic lymphocytic leukemia (CLL). (b) Smudge Cell:- -Also termed as basket cell. – these a…

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