Find genes in ALL with the most and the least significant effect on age – plot distribution of p-values for gene effect on age for all 12K genes, generate diagnostic plots and present model summaries and ANOVA results for the linear models of the two extreme cases – the gene with the most and with the least significant effect on age as assessed by ANOVA. Hint 1: quantify the effect strength by significance, not by the magnitude of the slope; Hint 2: anova is slow, running 12K times may take some time – debug you code on a subset of data, e.g. first 100 rows.
TO access ALL dataset go on R and do the following:
source(“http://www.bioconductor.org/biocLite.R”)
biocLite(ALL)
library (ALL)
data (ALL)
exprs(ALL)
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